ABSTRACT
Background:Various studies done in the past few decades have shown association of hyperuricemia with the increase in cardiovascular [CV] mortality
Objective: To determine the association of hyperuricemia and in hospital complications in acute coronary syndrome patients
Methodology: This cohort study was conducted on 154 patients in department of Cardiology Sheikh Zayed Medical College/Hospital, Rahim Yar Khan from 1st January to 30th June 2017. Hyperuricemia was defined as serum uric acid level >/= 7.2 mg/dl in males and serum uric level >/= 6 mg/dl in females.The data collection was started after getting informed consent of the patients admitted through accident and emergency department. Consecutive patients of acute coronary syndrome were selected and those with hyperuricemia were labeled as exposed [Group I] and those with normouricemia were considered as non-exposed [Group II]. The two groups were followed for 7 days and outcome i.e inhospital complications in terms of conduction defect and heart failure were noted as per operational definition. The data were collected on a proforma like age and sex. Effect modifiers like age, sex, family history of ACS, history of T2DM, history of hypertension, smoking and BMI were stratified to see the impact of these on outcomes. Chi square test were applied to determine the association of hyperuricemia with in hospital complications like conduction defect and heart failure. P value . 5% was taken as significant
Results: Among the total study subjects [n=154], 100[65%] were male and 54[35%] were female. The mean age and BMI of Group I [ACS with hyperuricemia] and Group II [ACS without hyperuricemia] were 65+/- 2 years vs. 62+/-11 years and BMI 27+/- 3.2 vs 25+/- 2.8 respectively. Out of 154 patients, 28 [18.1%] have conduction defect and only 40[26%] patients suffered heart failure. From these 28 patients with conduction defects, 19 [24.6%] were with ACS and hyperuricemia and 09[11.6%] were with ACS without hyperuricemia. From these 40 patients with heart failure,33 [42.8%]were with ACS and hyperuricemia and 07 [9%] were with ACS without hyperuricemia
Conclusion: This study showed that in-hospital complications were significantly higher in patients with ACS with hyperuricemia as compared to patients with ACS without hyperuricemia
ABSTRACT
Objective: To ascertain knowledge of modifiable risk factors about coronary artery disease in an urban male population of Sargodha city; Pakistan
Study Design: Observational / cross sectional study
Place and Duration of Study: This study was carried in urban male population of Sargodha city, Pakistan from November, 1[st] to 30[th] 2015
Materials and Methods: This study was carried out to recognize knowledge of modifiable risk factors about coronary artery disease in an urban male population of Sargodha city. All 100 married male apparently healthy participants; 25-60 years of age were included
Results: The mean age of subjects was 40.12 +/- 10.22 years. The frequency of smoking [28%] was significantly higher in study population, sedentary lifestyle [5%] obesity [22%], use of salt [17%] and use of fat [8%] respectively
Conclusion: The present study determines a poor knowledge of modifiable risk factors regarding Coronary artery disease in the urban male population. Therefore, there is an immediate need to initiate measures to raise awareness of these modifiable risk factors so that individuals at high risk for future Coronary artery disease can be managed
ABSTRACT
Objective: To determine frequency of modifiable risk factors about coronary artery disease in an urban female population of Sargodha city of Punjab province of Pakistan
Study Design: Descriptive / cross sectional study
Place and Duration of Study: This study was conducted at the urban female population of Sargodha city of Punjab province of Pakistan from March, 1[st] to 30[th] 2016
Materials and Methods: This study was carried out to identify frequency of modifiable risk factors about coronary artery disease in an urban female population of Sargodha city. All 100 married female apparently healthy participants; 25-60 years of age were included
Results: The mean age of subjects was 36.02 +/- 10.02 years. The frequency of smoking [27%] was expressively advanced in study population, sedentary lifestyle [19%] obesity [25%], use of salt [16%] and use of fat [13%] respectively
Conclusion: The current research concludes a reduced information related to modifiable threat aspects regarding coronary artery disease in the urban feminine populace. Consequently, there is a speedy prerequisite to initiate actions to educate peoples of this group in relation of changeable risk features so that those at high risk for upcoming patients of controllable coronary artery disease can be coped